Pharmacovigilance, automated

Your drug safety agent
never sleeps

SignalVault is an autonomous AI that monitors adverse events, detects safety signals, and files FDA/EMA reports — 24/7, without your team spending hours on manual case processing.

24/7 Continuous monitoring
85% Manual work eliminated
EMA GVP compliant output
The problem

Pharmacovigilance is still running on spreadsheets in 2026

Every pharma company is required by law to monitor drug safety. But most mid-market teams are buried in manual intake forms, case processing, and report writing — chasing signals that surface too late and missing filing deadlines that cost millions in warning letters.

$4.2M
Average FDA warning letter cost for PV violations
38%
Of safety signals detected too late for proactive action
200+
Hours/month spent on manual case processing per analyst
SignalVault — Live Monitoring
Drug: Amlopidine 10mg — No new signals detected Just now
Drug: Exavir-L — Potential hepatic signal flagged, 12 reports 4 min ago
Drug: Zanopen — Confirmed cardiac signal, FDA filing queued 11 min ago
Drug: Clevexis 25mg — Routine monitoring, all clear 23 min ago
Drug: Thorazine SR — Elevated GI reports, reviewing causality 1h ago
The agent

One agent replaces your entire PV analyst team

SignalVault ingests adverse event reports from all sources — EHR systems, patient portals, literature, social media. It triages by severity, detects emerging signals using medical NLP, generates causality assessments, and queues regulatory filings automatically.

  • Real-time signal detection from unstructured sources
  • Automatic PSMF, RMP, and PBRER generation
  • FDA ICH-E2D and EMA GVP Module IX compliant output
  • Continuous literature monitoring across 40+ journals
  • Escalation pathways for confirmed serious risks

How it works

01

Ingest

Adverse events flow in from EHR integrations, web portals, literature, and direct reports. SignalVault normalizes and structures every case automatically.

02

Detect

Medical NLP scans every report in real time. Emerging signals surface before they become crises — and before regulators find them for you.

03

Report

PSURs, RMPs, and signal narratives are drafted automatically in regulatory-ready format. Your team reviews and approves — doesn't write from scratch.

04

Comply

Every action is logged, time-stamped, and audit-ready. SignalVault maintains your compliance trail continuously — not just when an inspector shows up.

Compliance by design

Built for the regulators who will audit you

SignalVault is architected around FDA 21 CFR Part 11, EMA GVP modules, and ICH-E2D requirements from day one. Every signal detection is logged with full audit trail. Every AI-generated sentence is traceable to its source document.

FDA ICH-E2D
EMA GVP
21 CFR Part 11
ICH E2A-E2F
HIPAA Ready
Latest Audit Trail — Signal #4391
2026-05-27 08:14:02 UTC Signal detected: hepatic enzyme elevation, drug X
2026-05-27 08:14:08 UTC Causality assessment: probable (WHO-UMC scale)
2026-05-27 08:14:21 UTC PSUR draft generated, queued for review
2026-05-27 08:14:33 UTC Escalation: Internal Safety Review triggered
2026-05-27 08:15:01 UTC Full audit trail saved, tamper-evident hash: 0x8f3a...

The future of drug safety is autonomous. Is your company ready?

SignalVault is built for mid-market pharmaceutical companies who need real pharmacovigilance — not a spreadsheet, not a legacy enterprise contract, and not a team of analysts manually chasing signals in the dark.